Mechanism of Action
Ascophyllum nodosum works systemically rather than topically. After ingestion, bioactive compounds including polyphenols and fucoidan are absorbed through the digestive tract and excreted into saliva. These compounds inhibit the bacterial glucosyltransferase enzyme that facilitates plaque biofilm formation on tooth surfaces. The result is a reduction in bacterial adhesion and biofilm accumulation on teeth throughout the day. The compound also has anti-inflammatory properties that support gum health and helps soften existing plaque deposits over time.
Evidence Summary
Ascophyllum nodosum has the strongest clinical evidence base of any dietary supplement used for pet dental health. A 2018 double-blind, randomised, placebo-controlled trial published in Frontiers in Veterinary Science examined the effect of Ascophyllum nodosum powder in dogs over 90 days. The study found a 35 percent reduction in calculus index at day 30 that was sustained to day 90, and plaque accumulated significantly more slowly than on placebo, with a significant difference at day 90. Volatile sulfur compounds were 35 and 46 percent lower at days 60 and 90, both significant. Differences in the overall oral health index were not statistically significant.
In Petz Park Products
Plaque Control for Dogs: 1,000mg per scoop. Plaque Control for Cats: 500mg per scoop (lower dose calibrated for feline body weight).
Safety and Considerations
Ascophyllum nodosum contains natural iodine. It is not suitable for dogs or cats with thyroid disorders, as excess iodine can interfere with thyroid hormone regulation. Hyperthyroid cats, which are common in older cats, should not use Plaque Control for Cats. Confirm with a veterinarian before use in any animal with a known thyroid condition.
Used in These Products
Dog Products
Cat Products
Helps With These Concerns
Dog Health
Cat Health