--- title: "Schisandra Chinensis for Dogs and Cats | Petz Park" description: "Schisandra Chinensis — active ingredient in Petz Park supplements. Schisandra Chinensis in Petz Park supplements. Learn about the mechanism, evidence, and..." lang: en json-ld: | [ { "@context": "https://schema.org", "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://knowledge.petzpark.com.au" }, { "@type": "ListItem", "position": 2, "name": "Ingredients", "item": "https://knowledge.petzpark.com.au/ingredients" }, { "@type": "ListItem", "position": 3, "name": "Schisandra Chinensis", "item": "https://knowledge.petzpark.com.au/ingredients/schisandra-chinensis" } ] }, { "@context": "https://schema.org", "@type": "MedicalWebPage", "name": "Schisandra Chinensis", "description": "Schisandra Chinensis for Dogs and Cats | Petz Park", "url": "https://knowledge.petzpark.com.au/ingredients/schisandra-chinensis", "about": { "@type": "Substance", "name": "Schisandra Chinensis" }, "publisher": { "@type": "Organization", "name": "Petz Park", "url": "https://petzpark.com.au" } }, { "@context": "https://schema.org", "@type": "ItemList", "name": "Products containing Schisandra Chinensis", "itemListElement": [ { "@type": "ListItem", "position": 1, "url": "https://knowledge.petzpark.com.au/dogs/products/liver-support-for-dogs", "name": "Liver Support for Dogs" }, { "@type": "ListItem", "position": 2, "url": "https://knowledge.petzpark.com.au/cats/products/liver-support-for-cats", "name": "Liver Support for Cats" } ] } ] --- [![Petz Park logo](/images/petz-park-logo.png)](https://www.petzpark.com.au/?utm_source=knowledgecentre&utm_medium=ingredient_article&utm_campaign=schisandra_chinensis&utm_content=navigation) [Home](/) [Dogs](/dogs) [Cats](/cats) [Products](/products)[Ingredients](/ingredients)[Comparisons](/comparisons)[FAQs](/faqs)[Trust & Proof](/trust) About [Visit Store](https://petzpark.com.au/?utm_source=knowledgecentre&utm_medium=ingredient_article&utm_campaign=schisandra_chinensis&utm_content=header_cta) 1. [Home](/) 3. [Ingredients](/ingredients) 5. Schisandra Chinensis # Schisandra Chinensis Schisandra chinensis (Wu Wei Zi, Five Flavour Berry) is a medicinal vine native to northern China and eastern Russia. Of the three ingredients in Petz Park Liver Support, it has the most direct comparison to established veterinary hepatoprotective treatments: Petz Park's own product page notes that Schisandra Chinensis Extract and SAMe (the primary active in Hepatoadvanced and Denamarin, the most widely prescribed veterinary liver supplements) both reduce oxidative stress in the liver through different molecular pathways. ## Mechanism of Action Schisandra's active lignans, particularly schisandrin B and schisandrin C, operate through multiple hepatoprotective mechanisms. They reduce lipid peroxidation in hepatocyte membranes, protecting liver cells from oxidative damage. They upregulate hepatic glutathione synthesis, increasing the liver's primary endogenous antioxidant capacity. They reduce activation of NF-kB, a master regulator of hepatic inflammation, lowering the production of TNF-alpha and IL-6 in liver tissue. They also stimulate hepatocyte proliferation through effects on growth factor signalling, supporting the liver's capacity for tissue regeneration after injury. ## Evidence Summary Schisandra has been studied extensively in animal models of chemically induced liver injury. A review published in Molecules (2012) documented schisandrin B's protective effects against carbon tetrachloride, paracetamol and thioacetamide-induced liver damage in rodent models, with significant reductions in ALT and AST enzyme levels. A 2019 study in the Journal of Ethnopharmacology confirmed hepatoprotective and antifibrotic effects of schisandrin B in a high-fat diet rodent model. Petz Park's direct comparison to Hepatoadvanced and Denamarin on their product page is honest and accurate: Schisandra provides hepatoprotection through a complementary pathway to SAMe. ## In Petz Park Products Liver Support for Dogs: Schisandra Chinensis 220mg per scoop. Liver Support for Cats: Schisandra Chinensis Extract 50mg per scoop. ## Safety and Considerations Schisandra is well tolerated at supplemental doses in dogs and cats. It may modestly affect the hepatic metabolism of some drugs processed through CYP3A4 pathways. Veterinary oversight is recommended for animals with diagnosed liver disease receiving prescription hepatic treatments. ## Used in These Products Dog Products - [Liver Support for Dogs](/dogs/products/liver-support-for-dogs) Cat Products - [Liver Support for Cats](/cats/products/liver-support-for-cats) ## Helps With These Concerns Dog Health - [Liver Health for Dogs](/dogs/liver-health) Cat Health - [Liver Health for Cats](/cats/liver-health) [Back to Ingredients](/ingredients) Explore the Knowledge Centre - [All Ingredients](/ingredients) - [Dog Supplements](/dogs) - [Cat Supplements](/cats) - [Knowledge Centre Home](/) ![Petz Park](/images/petz-park-logo.png) Australian-made pet supplements for dogs and cats. ### Explore - [Home](/) - [Dogs](/dogs) - [Cats](/cats) - [Products](/products) - [Ingredients](/ingredients) - [Comparisons](/comparisons) - [FAQs](/faqs) - [About](/about) - [Trust & Proof](/trust) ### Dog Health - [Joint Health for Dogs](/dogs/joint-health) - [General Health and Vitality for Dogs](/dogs/general-health-vitality) - [Urinary and Kidney Health in Dogs](/dogs/urinary-kidney-health) - [Probiotics for Dogs](/dogs/probiotics) - [Liver Health for Dogs](/dogs/liver-health) - [Skin, Coat and Allergies in Dogs](/dogs/skin-coat-allergies) - [Brain and Cognitive Health in Dogs](/dogs/brain-cognitive-health) - [Anxiety and Stress in Dogs](/dogs/anxiety) - [Eye Health for Dogs](/dogs/eye-health) - [Dental Health for Dogs](/dogs/dental-health) - [Senior Dog Health](/dogs/senior-dog-health) - [Immune and Seasonal Health for Dogs](/dogs/immune-seasonal-health) ### Cat Health - [Joint Health for Cats](/cats/joint-health) - [Anxiety and Stress in Cats](/cats/anxiety) - [Dental Health for Cats](/cats/dental-health) - [Liver Health for Cats](/cats/liver-health) - [Skin, Coat and Allergies in Cats](/cats/skin-coat-allergies) - [General Health and Vitality for Cats](/cats/general-health-vitality) - [Urinary and Kidney Health in Cats](/cats/urinary-kidney-health) - [Eye Health for Cats](/cats/eye-health) - [Probiotics for Cats](/cats/probiotics) ### Contact - [petzpark.com.au](https://petzpark.com.au/?utm_source=knowledgecentre&utm_medium=ingredient_article&utm_campaign=schisandra_chinensis&utm_content=navigation) [Instagram](https://www.instagram.com/petzpark "Instagram")[Facebook](https://www.facebook.com/petzpark "Facebook")[TikTok](https://www.tiktok.com/@petzpark "TikTok") © 2026 Petz Park. 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